FLEA and TICK MEDICATIONS @ Vet.com

Advantage for dogs and cats,K9 advantix,Sentinel, Program, Frontline Plus, Heartguard,Interceptor, and Revolution. Direct information and comparisons for you and your pet on the most popular consumer available flea and tick medications.

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DOG MEDS:
Advantage
Program Tabs
K9 Advantix
Frontline Plus
Interceptor
Revolution
Heartguard

INTERCEPTOR Flavor Tabs are the only monthly preventive that protects against four parasites all at once. INTERCEPTOR prevents deadly heartworm disease, while it protects your dog against adult roundworms, adult hookworms (A. caninum) and whipworms.

Information for dosing dogs
The palatable once-a-month tablet that prevents heartworm disease, controls adult hookworm, and removes and controls adult roundworm and whipworm infections in dogs and puppies.
Caution
U.S. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Description
INTERCEPTOR (milbemycin oxime) Flavor Tabs are available in four tablet sizes in color-coded packages for oral administration to dogs and puppies. Each tablet is formulated to provide a minimum of 0.23 mg/lb (0.5 mg/kg) body weight of milbemycin oxime. Milbemycin oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio of approximately 80% A4 (C32H45NO7, MW 555.71) and 20% A3 (C31H43NO7, MW 541.68).

Indications
INTERCEPTOR Flavor Tabs are indicated for use in the prevention of heartworm disease caused by Dirofilaria immitis, the control of adult Ancylostoma caninum (hookworm), and the removal and control of adult Toxocara canis and Toxascaris leonina (roundworms) and Trichuris vulpis (whipworm) infections in dogs and in puppies four weeks of age or greater, and two pounds body weight or greater.

Dosage
INTERCEPTOR Flavor Tabs are given orally, once a month, at the recommended minimum dosage rate of 0.23 mg milbemycin oxime per pound of body weight (0.5 mg/kg).

Administration
INTERCEPTOR Flavor Tabs are palatable and most dogs will consume the tablet willingly when offered by the owner. As an alternative, the dual-purpose tablet may be offered in food or administered as other tablet medications. Watch the dog closely following dosing to be sure the entire dose has been consumed. If it is not entirely consumed, redose once with the full recommended dose as soon as possible.

INTERCEPTOR Flavor Tabs must be administered monthly, preferably on the same date each month. The first dose should be administered within one month of the dog's first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. If a dose is missed and a 30-day interval between dosing is exceeded, administer INTERCEPTOR Flavor Tabs immediately and resume the monthly dosing schedule.

If INTERCEPTOR Flavor Tabs replaces diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

Palatability
Palatability trials conducted in 244 dogs from 10 different U.S. veterinary practices demonstrated that INTERCEPTOR Flavor Tabs were willingly accepted from the owner by over 95% of dogs. The trial was comprised of dogs representing 60 different breeds and both sexes, with weights ranging from 2.1 lbs. to 143.3 lbs., and ages ranging from 8 weeks to 15 years.
Precautions

Do not use in puppies less than four weeks of age and less than two pounds of body weight. Prior to initiation of the INTERCEPTOR Flavor Tabs treatment program, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with INTERCEPTOR Flavor Tabs. Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some treated dogs carrying a high num-ber of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae.

Adverse Reactions
The following adverse reactions have been reported following the use of INTERCEPTOR: Depression/ lethargy, vomiting, ataxia, anorexia, diarrhea, convulsions, weakness and hypersalivation.

Efficacy
INTERCEPTOR Flavor Tabs eliminate the tissue stage of heartworm larvae and the adult stage of hookworm (Ancylostomacaninum), roundworms (Toxocara canis, Toxascaris leonina) and whipworm (Trichuris vulpis ) infestations when administered orally according to the recommended dosage schedule. The anthelmintic activity of milbemycin oxime is believed to be a result of interference with invertebrate neurotransmission.

Safety
INTERCEPTOR has been tested safely in over 75 different breeds of dogs, including collies, pregnant females, breeding males and females, and puppies over two weeks of age. In well-controlled clinical field studies, 786 dogs completed treatment with milbemycin oxime. Milbemycin oxime was used safely in animals receiving frequently used veterinary products such as vaccines, anthelmintics, antibiotics, steroids, flea collars, shampoos and dips.

Two studies in heartworm-infected dogs were conducted which demonstrated mild, transient hypersensitivity reactions in treated dogs with high microfilaremia counts (see Precautions for reactions observed). Safety studies in pregnant dogs demonstrated that high doses (1.5 mg/kg = 3X) of milbemycin oxime given in an exaggerated dosing regimen (daily from mating through weaning), resulted in measurable concentrations of the drug in milk. Puppies nursing these females which received exaggerated dosing regimens demonstrated milbemycin-related effects.These effects were directly attributable to the exaggerated experimental dosing regimen. The product is normally intended for once-a-month administration only. Subsequent studies included using 3X daily from mating to one week before weaning and demonstrated no effects on the pregnant females or their litters. A second study where pregnant females were dosed once at 3X the monthly use rate either before, on the day of or shortly after whelping resulted in no effects on the puppies.

Some nursing puppies, at 2, 4, and 6 weeks of age, given greatly exaggerated oral INTERCEPTOR doses (9.6 mg/kg = 19X) exhibited signs typified by tremors, vocalization and ataxia. These effects were all transient and puppies returned to normal within 24 to 48 hours. No effects were observed in puppies given the recommended dose of INTERCEPTOR (0.5 mg/kg). This product has not been tested in dogs less than 1 kg weight.

A rising-dose safety study conducted in roughcoated collies manifested a clinical reaction consisting of ataxia, pyrexia and periodic recumbency in one of fourteen dogs treated with milbemycin oxime at 12.5 mg/kg (25X monthly use rate). Prior to receiving the 12.5 mg/kg dose (25X monthly use rate) on day 56 of the study, all animals had undergone an exaggerated dosing regimen consisting of 2.5 mg/kg milbemycin oxime (5X monthly use rate) on day 0, followed by 5.0 mg/kg (10X monthly use rate) on day 14 and 10.0 mg/kg (20X monthly use rate) on day 32. No adverse reactions were observed in any of the collies treated with this regimen up through the 10.0 mg/kg (20X monthly use rate) dose.

How Supplied
INTERCEPTOR Flavor Tabs are available in four tablet sizes (see Dosage section), formulated according to the weight of the dog. Each tablet size is available in color-coded packages of 6 or 12 tablets each, which are packaged 10 per display carton.

Storage Conditions
INTERCEPTOR Flavor Tabs should be stored at room temperature, between 59° and 86°F (15-30°C).

Keep this and all drugs out of the reach of children.

Preventitive Medications:

PROGRAM -prevent flea eggs and larvae from developing. This breaks the flea life cycle at its base, and effectively controls the flea population.

FRONTLINE -brand products is the longest-lasting, most complete product for controlling fleas and ticks. FRONTLINE for dogs and cats is highly effective, easy to use and provides superior, guaranteed protection. What's more, FRONTLINE is available in three convenient formulations to make it easy for you to protect your pet.

SENTINEL -there are five nasty parasites that threaten your dog: fleas, heartworms, hookworms, roundworms and whipworms. Only SENTINEL® Flavor Tabs® can protect against all five parasites at once.

HEART GUARD -Heartworm disease is 100% preventable with HEARTGARD Plus! All you have to do to protect your dog from the threat of this deadly infection is to give HEARTGARD Plus once a month and use as otherwise directed.

INTERCEPTOR -prevents deadly heartworm disease, while it protects your dog against roundworms, hookworms (A. Caninum) and whipworms.

ADVANTAGE -Because it works so fast, Advantage provides relief from fleas within minutes. Advantage is proven to stop fleas from biting in 3 - 5 minutes after application. Advantage kills 98-100 percent of fleas within 12 hours of application. In addition, one convenient treatment lasts for up to one month.

REVOLUTION -Revolution is the first-ever FDA approved, topically-applied medication for both dogs and cats that: Prevents heartworm (Dirofilaria immitis) disease, Kills adult fleas (Ctenocephalides felis) and prevents their eggs from hatching, Treats and controls ear mites (Otodectes cynotis), Treats and controls sarcoptic mange (Sarcoptes scabiei) in dogs, Treats hookworm (Ancylostoma tubaeforme) and roundworm (Toxocara cati) in cats, Controls American dog tick (Dermacentor variabilis) infestations in dogs.

K9ADVANTIX -Is your dog being attacked by mosquitoes, ticks and fleas? If you are looking for information on the only product that can keep mosquitoes, ticks and fleas off your four-legged friend then you’ve come to the right place. At K9Advantix.com we’ll provide you with the information you’ll need to rid your dog of these pests forever!

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IVENTURE 2009