Advantage for dogs and cats,K9 advantix,Sentinel, Program, Frontline Plus, Heartguard,Interceptor, and Revolution. Direct information and comparisons for you and your pet on the most popular consumer available flea and tick medications.

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Program Tabs
Program 6
Frontline Plus


The six-month injection that controls flea populations in cats.

U.S. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

PROGRAM® (lufenuron) 6 Month Injectable for Cats is available in two syringe sizes for subcutaneous administration to cats and kittens according to their weight. (See Dosage.) Each preloaded syringe is formulated to provide 4.54 mg/pound (10 mg/kg) body weight of lufenuron. The active ingredient of PROGRAM 6 Month Injectable for Cats is lufenuron, a benzoylphenyl-urea derivative with the following chemical composition: N-[2,5-dichloro-4-(1,1,2,3,3,3,-hexafluoropropoxy)-phenyl-aminocarbonyl]-2, 6-difluorobenzamide. Benzoylphenyl-urea compounds, including lufenuron, are classified as insect development inhibitors (IDIs).

Mode of Action
Lufenuron, the active ingredient of PROGRAM 6 Month Injectable for Cats, is an insect development inhibitor which breaks the flea life cycle by inhibiting egg development. Lufenuron's mode of action is interference with chitin synthesis, polymerization and deposition. Lufenuron has no effect on adult fleas.
After biting a lufenuron-treated cat, the female flea ingests a blood meal containing lufenuron which is subsequently deposited in her eggs. Lufenuron prevents flea eggs from hatching and developing into adults and thus controls flea populations by breaking the life cycle. (See Efficacy.)

PROGRAM 6 Month Injectable for Cats is indicated for use in cats, six weeks of age and older, for the control of flea populations.
Lufenuron controls flea populations by preventing the development of flea eggs and does not kill adult fleas. Concurrent use of insecticides may be necessary for adequate control of adult fleas.

Do not use in dogs. A severe local reaction may occur in dogs that is not seen in cats.

The safety of PROGRAM 6 Month Injectable for Cats in reproducing animals has not been established.

PROGRAM 6 Month Injectable for Cats breaks the flea life cycle by inhibiting egg development. However, pre-existing flea populations may continue to develop and emerge after treatment with PROGRAM 6 Month Injectable for Cats. Based on results of clinical studies, this emergence generally occurs during the first 30-60 days. Therefore, noticeable control may not be observed until several weeks after dosing when a pre-existing infestation is present. Cooler geographic areas may have longer lag periods due to a prolonged flea life cycle. Insecticides may be used concurrently depending on the severity of the infestation.

Preventitive Medications:

INTERCEPTOR FLAVOR TABS for cats -the only oral monthly preventative that protect against heartworms and remove adult roundworms (Toxocara cati) and adult hookworms (Ancylostoma tubaeforme).

PROGRAM FLAVOR TABS and PROGRAM SUSPENSION -both prevent flea eggs and larvae from developing. This breaks the flea life cycle at its base, and effectively controls the flea population.

PROGRAM 6 MONTH INJECTION for CATS -prevents flea eggs and larvae from developing. This breaks the flea life cycle at its base, and effectively controls the flea population.

FRONTLINE -brand products is the longest-lasting, most complete product for controlling fleas and ticks. FRONTLINE for dogs and cats is highly effective, easy to use and provides superior, guaranteed protection. What's more, FRONTLINE is available in three convenient formulations to make it easy for you to protect your pet.

ADVANTAGE -Because it works so fast, Advantage provides relief from fleas within minutes. Advantage is proven to stop fleas from biting in 3 - 5 minutes after application. Advantage kills 98-100 percent of fleas within 12 hours of application. In addition, one convenient treatment lasts for up to one month.

REVOLUTION -Revolution is the first-ever FDA approved, topically-applied medication for both dogs and cats that: Prevents heartworm (Dirofilaria immitis) disease, Kills adult fleas (Ctenocephalides felis) and prevents their eggs from hatching, Treats and controls ear mites (Otodectes cynotis), Treats hookworm (Ancylostoma tubaeforme) and roundworm (Toxocara cati) in cats.

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